5-Aza-CdR delivers a gene body blow.

نویسندگان

  • Sivakanthan Kasinathan
  • Steven Henikoff
چکیده

In this issue of Cancer Cell, Yang et al. describe a causal relationship between gene body methylation and gene expression and a role for genic methylation in response to clinical DNA methylation inhibitors, which suggests that the mechanism of action of these inhibitors includes gene body hypomethylation-induced downregulation of cancer-associated genes.

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عنوان ژورنال:
  • Cancer cell

دوره 26 4  شماره 

صفحات  -

تاریخ انتشار 2014